IP Antibiotic Tool — PD Peritonitis
Dosis intraperitoneal (intermittent vs continuous), teknik pemberian, dan kompatibilitas. Berbasis ISPD 2022 Peritonitis Guideline.
ISPD 2022💊 IP Antibiotic Tool — PD Peritonitis
Intermittent vs continuous • teknik pemberian • kompatibilitas
Kalkulator dosis IP
Tekan Hitung.
Safety checks
APD ≠ CAPD. ISPD tidak menganjurkan ekstrapolasi dosis CAPD ke APD; dwell pendek dapat menyebabkan underdosing.
Vancomycin: dwell minimal sekitar 4 jam; sekitar 6 jam lebih rasional bila memungkinkan. Redosing sebaiknya berbasis level + modality + respons.
Tool edukasional. Verifikasi dosis, compatibility, dwell, residual kidney function, kultur/MIC, antibiogram, alergi, dan protokol nefrologi/farmasi sebelum order.
Regimen ISPD 2022
| Obat | Intermittent | Continuous |
|---|---|---|
| Cefazolin | 15 mg/kg daily long dwell; 20 mg/kg short dwell | LD 500 mg/L; MD 125 mg/L |
| Ceftazidime | 1000–1500 mg daily long dwell; 20 mg/kg short dwell | LD 500 mg/L; MD 125 mg/L |
| Cefepime | 1000 mg daily | LD 500 mg/L; MD 125 mg/L |
| Gentamicin | 0.6 mg/kg daily | Not advised |
| Amikacin | 2 mg/kg daily | Not advised |
| Vancomycin | CAPD 15–30 mg/kg q5–7d; APD 15 mg/kg q4d | LD 20–25 mg/kg; MD 25 mg/L |
| Meropenem | 500 mg daily long dwell APD; 1000 mg daily short dwell CAPD | MD 125 mg/L |
Educational clinical tool — bukan pengganti clinical judgment. Basis dosis: ISPD 2022 Table 5 dan bagian Special Considerations for APD.